PGT
(Preimplantation Genetic Testing)
GenoBro is an NGS-based PGT (pre-implantation test) test that selects genetically normal embryos. It has a much higher sensitivity and suspend time than conventional methods (FISH, aCGH) and can shorten inspection time.
Increased implantation and pregnancy success rates and elimination of embryos with chromosomal abnormalities can reduce abortion rate.
WHAT is
PGT?
Preimplantation genetic testing (PGT) is a
technique that allows embryos to be
genetically tested prior to being transferred
into a woman’s uterus for the purpose of
establishing a healthy pregnancy. PGT allows
embryos at risk for chromosomal or genetic
conditions to be identified as healthy before
they are selected for embryo transfer.
WHO need
PGT?
-
Women who plan to have children when they
are older (over 35 years of age) -
Women who have had recurrent pregnancy
loss and/or earlier embryo implantation failure
in two or more cycles of in vitro fertilisation -
Patients with chromosomal abnormality diagnoses
-
Couples in which a severe male factor has
been identified as a cause of infertility.
PGT
PRINCIPLE
After the in vitro fertilization, the embryo is harvested from 3 to 5 days after the amplification of the DNA, and then analyzed by using the next generation genome sequencing technology, which is the latest analysis technology, to analyze the chromosome abnormality more quickly and accurately. Because of this principle, the Embryos with normal chromosomes can be screened.